Development of a DNA Test

Some Jack Russell Terriers (JRTs) suffer from a progressive neonatal cerebellar ataxia that differs from a previously reported spinocerebellar ataxia in this breed. Serial neurologic examinations of affectedp ups revealed normal mentation, intention tremors and severe gait, stance and ocular ataxia beginning at 2 weeks of age. A dancing gait, hypometria in all limbs, decrease ...

Ataxia

Submitted by Debbie Johnson It has been almost 20 years since I first experienced Cerebellar Ataxia. I had spent several years acquiring a number of quality working bitches before I decided to purchase a stud dog that would compliment my acquired bitch’s pedigrees. Before long my first resulting litter whelped, I still remember the feeling ...

Ataxia in the Jack Russell Terrier

Cerebellar Ataxia a.k.a. neonatal cerebellar ataxia, primary granule cell degeneration Onset of signs – 2 weeks of age when pups begin to ambulate Neurologic abnormalities – An uncoordinated gait, spastic in all limbs, start out as a goose-stepping stride which progresses to a stilted stride in all limbs.  Dogs develop more difficulty in forward ambulation ...

Degenerative Myelopathy

Dr Joan Coates & Dr Gary Johnson & associates (University of Missouri) in collaboration with Drs Claire Wade & Kirsten Lindblad-Toh & associates (Broad Institute at MIT) identified a mutation that is the primary risk factor for Degenerative Myelopathy (DM) in many breeds of dogs. A DNA test for this disorder has been available since ...

Two Types of Ataxia

There are two types of ataxia in the Jack Russell Terrier, Cerebellar Ataxia and Spino-Cerebellar Ataxia, also referred to as SCA. These are two different genetic diseases, and at this time, we only have a genetic test for SCA. Cerebellar Ataxia This type of Ataxia is often referred to as Early Onset Ataxia and affects ...

Nutritional Cataracts

By Dr. Lisa Meek, Member ACVO A nutritional cataract is caused by either a deficiency or excess of a nutrient resulting in a loss of transparency of the lens. Nutritional cataracts have been identified in various species, including rats, pigs, wolves, fish and guinea pigs as well as dogs and cats. In dogs and cats ...

Canine Cataracts

Definition of Cataracts The word cataract literally means ‘to break down’. This breakdown refers to the disruption of the normal arrangement of the lens fibers or its capsule, which results in the loss of the transparency of the lens and a reduction in vision. Cataracts often appear to have a white or crushed ice appearance ...

Ataxia from a Breeders Standpoint

For those who have never experienced the tragedy of spinocerebellar (late onset) ataxia, I would like to tell my experiences. My litter (of 3) were born healthy with no whelping problems, but at 9 wks of age I began to notice that one of the pups was moving like each leg was a different length. ...

Spinocerebellar Ataxia with Myokymia: Facts

Ataxia: JRTs can be affected with Cerebellar Ataxia OR Spinocerebellar Ataxia. Not both. It is not the norm for an entire litter of 4 to be affected with ataxia. Usually its one or two… but, as with all diseases… one never knows for sure. Cerebellar Ataxia (early onset): Age at onset 2 weeks (or as ...

What is Glaucoma?

There are 2 classifications of glaucoma – Primary and Secondary. Primary glaucoma occurs without previous trauma or ocular disease, and will eventually affect both eyes. Secondary glaucoma is a consequence of some other disease, such as ocular inflammation, lens dislocation, intraocular tumors, or trauma. My first reaction was this can’t be primary as the numbers ...